The cannabinoid activities in the hypothalamus affect the appetite and the food-seeking behavior. However, when the endocannabinoids’ concentrations are high, it can increase the risk of obesity. Cannabidiol can inverse the effects of the endocannabinoids on weight gain. It regulates hunger and controls cravings. It also regulates insulin sensitivity which can greatly help in alleviating diabetes and its symptoms.
The substance can significantly enhance many metabolic functions such as nutrient support and energy storage. It improves the performance of the small intestines, skeletal muscles, and pancreas. It is also significant in treating atherosclerosis and other cardiovascular diseases.
Obesity is just one of the medical conditions prevalent in modern society. It is a medical condition in which the human body accumulates too much fat to the extent that it can cause numerous health issues and even death. Obesity can be determined by checking the person’s body mass index or BMI. It is a method that measures the person’s weight and height in order to determine whether he or she is overweight. A person who has a BMI ranging between 25 and 30 kg/m2 is considered overweight while those who have a BMI beyond the 30 kg/m2 are considered obese. This article will discuss the correlation between cannabinoids and obesity.
Obesity and CBD Cannabidiol
Several studies have revealed that cannabis can be used to help treat obesity. THCV and cannabidiol are just two of the compounds found in cannabis leaves that are known to improve the body’s ability to burn energy. Various medical institutions have conducted tests in mice and the results showed that the two compounds were effective in treating type 2 diabetes, obesity, and metabolic syndrome.
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The American Journal of Medicine published an observational trial data in 2013, talking about the efficacy of cannabis in fighting obesity. The result showed that subjects who used cannabinoids were able to take control of their diabetes problem compared to those who had no history of using cannabinoids as a form of medication.
In 2012, the British Medical Journal published separate tests. The results show that those who consumed cannabinoids had lower tendencies of acquiring type 2 diabetes than those who didn’t. Similarly, the American Journal of Epidemiology published a cross-sectional data in 2011, stating that the obesity was sharply lower among the population who consumed marijuana compared to nonusers.
Another popular study is the preclinical study data released by the Nutrition & Diabetes, a reputable scientific journal. The reports state that tetrahydrocannabivarin or THCV comes with a positive metabolic effect on animal test subjects. According to the British researchers involved in the said study, the effects of THVC had a positive impact to obese mice that were genetically modified. Although no significant changes were noticed in terms of the subjects’ body weight gain or food intake, the subjects were able to reduce their glucose tolerance, insulin sensitivity, and liver triglyceride while reducing glucose intolerance.
Cannabinoids and Hemp Oil
Until now, many medical institutions are still conducting numerous studies on cannabinoids and hemp oil. Once the true potential of cannabinoid has been exploited, it will be a huge discovery in the medical industry. It will pave the way for a newer generation of medicines and help treat diseases that were once deemed incurable.
Cannabidiol Research: Obesity
- Cannabinol and cannabidiol exert opposing effects on rat feeding patterns
- The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
- Cannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?
- The endocannabinoid system in obesity and type 2 diabetes
- Role of the endocannabinoid system in abdominal obesity and the implications for cardiovascular risk
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
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