Diseases that cause a person to experience immediate allergic reactions are referred to as atopic diseases. One good example of an atopic disease is asthma. Atopic diseases are common in many countries, especially in the developed nations, and they affect 20 percent of the country’s total population. This article will tackle how CBD, Cannabidiol, a well-known non-psychoactive Cannabinoid produced from the hemp plant, treats atopic diseases like asthma. It is known for treating numerous medical conditions.
In order to eliminate these public health problems, numerous medical institutions and researchers conducted numerous examinations to study how cannabidiol or CBD can be utilized to combat atopic diseases like asthma. Although the majority of the studies conducted made use of rats as test subjects, the tests yielded encouraging results. According to the early research, it shows that Cannabidiol is one of the most effective treatments for alleviating the inflammation experienced by many people suffering from asthma.
For the research, medical experts made use of rats procured from a breeding facility as approved by the Universidade do Extremo Sul Catarinense’s Ethics Committee in Brazil. The subjects were kept in a cage for safekeeping. The subjects where then exposed to light in an interval of 12 hours. The rats were also given proper food and water at their disposal.
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The subjects were also administered with chicken ovalbumin or OVA that comes with or without aluminum hydroxide. This is because OVA is considered unconventional to the environment and can provoke Th2 and Tp responses. After 14 days, the second administration of aluminum hydroxide was carried out. During the last two days of the study, 21 of the subjects were categorized into three different groups composed of a control group, an OVA-administered asthma group, and the last group would be the asthma/treatment group injects with both OVA and Cannabidiol.
The asthma group were injected with a solution of CBD, Cannabidiol and TWEEN®80 once per day. The said solution was prepared prior to administering it to the subjects. It is also important that the solution was kept out of light before the procedure. After 24 hours, it is critical that the subjects provide blood samples in order for the research to study their cytokine level. Cytokines refer to the small proteins secreted by cells that play a crucial role in the behavior of cells and the way they interact with each other.
After the study, it was concluded that the test subjects administered with CBD, Cannabidiol experienced a considerable reduction of Th2 and Tp, both of which are known as types of cytokines. Aside from the positive results brought about by CBD treatment when it comes to reducing levels of cytokine, the study also suggests that Cannabidiol can reduce other known symptoms experienced by many asthma sufferers such as mucus hypersecretion.
The results of the study coincide with that of the results produced by the Ribeiro study published in the European Journal of Pharmacology in the year 2012. The said study shows that Cannabidiol comes with potent anti-inflammatory and immunosuppressive properties. Although Cannabidiol’s efficiency as a non-psychoactive Cannabinoid is still in question, recent studies have clearly shown that using hemp oil to cure diseases is possible in the future.
Cannabidiol Research: Asthma
- The role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain and ischemic stroke
- Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma
- Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs
- Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways
- Bronchodilator effect of delta1-tetrahydrocannabinol
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