Today, neurodegenerative disorders represent one of the leading causes of death in the developed nations. These disorders are exemplified by a loss of neurons in certain areas of the nervous system. This loss of nerve cells is believed to trigger subsequent weakening in motor and cognitive functions that patients with these disorders go through.
Inflammation, the common denominator among the neurodegenerative disorders, is linked to be a critical component responsible for the development of neurodegeneration. There are a few treatments for these diseases, but scientists are still doing research on new therapeutic methods. In this light, cannabis derivatives have drawn some interest, but these compounds often raise ethical and practical issues for their potential abuse. However, among compounds present in cannabis, CBD/Cannabidiol, which is lacking of undesirable psychotropic effect, might have a promising component with the highest possibility for therapeutic use.
Clinical Studies on CBD About Neurodegenerative Disorders
The current information on Cannabidiol (CBD) use in clinical research has been reviewed, triggering the potential of CBD to prevent neurodegenerative diseases and to manage the symptoms associated with these pathologies. While the scope of the clinical effect of CBD is impressive, the molecular process through which CBD/Cannabidiol exerts its action is still vague. Because of that, this phytocannabinoid might stand in as a primary compound for the advancement of therapeutics that can exert neuroprotection and function against neuroinflammatory element of neurodegenerative diseases.
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Neuroinflammation, a major symptom of various neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), has been associated in the structures responsible for such diseases. As a matter of fact, if there is no neuroinflammation, recovery from injuries and elimination of offending components may be possible because over activated astrocytes and microglia generate countless substances that open up the possibility of self-propagating processes that urge the chronic development of neurodegenerative disorders.
CBD Relief and ALS
ALS (amyotrophic lateral sclerosis) is a deadly neurodegenerative disorder characterized by selective loss, which implicates motoneurons in the spinal cord, brainstem, and cortex. Because studies validate the connection of oxidative stress and neuroinflammation in the pathophysiology of ALS, it is then possible to recommend that due to the antioxidative and anti-inflammatory properties of CBD/Cannabidiol, it can be a promising course of action to treat symptoms or at least prolong the life expectancy of ALS patients. This research is backed by the study that CBD and other components of cannabis improve the symptoms of ALS patients.
Cannabidiol Research: ALS
- Cannabis and amyotrophic lateral sclerosis
- Medical Cannabis Helps ALS Patient Outlive her Own Doctor
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